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» Intuniv side effects in adults


Guanfacine Meets Phase 3 Endpoints for ADHD in Adults


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Intuniv (guanfacine)

Gynecomastia, transient elevation of blood glucose or serum creatine phosphokinase, and weight gain. The mechanism of this interaction is unknown, although both guanfacine and valproic acid are metabolised by glucuronidation, possibly resulting in competitive inhibition. In long-term, open-label studies, mean exposure of approximately 10 months , maximum decreases in systolic and diastolic blood pressure occurred in the first month of therapy. Company contact details Shire Pharmaceuticals Limited. Tolerance to the antihypertensive effect may develop in some patients, necessitating a reevaluation of therapy.

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